Submitted by admin on Tue, 03/24/2020 - 13:45
CDC Sanitizing Report
The literature contains several accounts of the properties, germicidal effectiveness, and potential uses for stabilized hydrogen peroxide in the health-care setting. Published reports ascribe good germicidal activity to hydrogen peroxide and attest to its bactericidal, virucidal, sporicidal, and fungicidal properties 653-655. (Tables 4 and 5) The FDA website lists cleared liquid chemical sterilants and high-level disinfectants containing hydrogen peroxide and their cleared contact conditions.
Hydrogen peroxide works by producing destructive hydroxyl free radicals that can attack membrane lipids, DNA, and other essential cell components. Catalase, produced by aerobic organisms and facultative anaerobes that possess cytochrome systems, can protect cells from metabolically produced hydrogen peroxide by degrading hydrogen peroxide to water and oxygen. This defense is overwhelmed by the concentrations used for disinfection 653, 654.
Hydrogen peroxide is active against a wide range of microorganisms, including bacteria, yeasts, fungi, viruses, and spores 78, 654. A 0.5% accelerated hydrogen peroxide demonstrated bactericidal and virucidal activity in 1 minute and mycobactericidal and fungicidal activity in 5 minutes 656. Bactericidal effectiveness and stability of hydrogen peroxide in urine has been demonstrated against a variety of health-care–associated pathogens; organisms with high cellular catalase activity (e.g., S. aureus, S. marcescens, and Proteus mirabilis) required 30–60 minutes of exposure to 0.6% hydrogen peroxide for a 108reduction in cell counts, whereas organisms with lower catalase activity (e.g., E. coli, Streptococcus species, and Pseudomonas species) required only 15 minutes’ exposure 657. In an investigation of 3%, 10%, and 15% hydrogen peroxide for reducing spacecraft bacterial populations, a complete kill of 106 spores (i.e., Bacillus species) occurred with a 10% concentration and a 60-minute exposure time. A 3% concentration for 150 minutes killed 106 spores in six of seven exposure trials 658. A 10% hydrogen peroxide solution resulted in a 103 decrease in B. atrophaeus spores, and a ≥105 decrease when tested against 13 other pathogens in 30 minutes at 20°C 659, 660. A 3.0% hydrogen peroxide solution was ineffective against VRE after 3 and 10 minutes exposure times 661 and caused only a 2-log10 reduction in the number of Acanthamoeba cysts in approximately 2 hours 662. A 7% stabilized hydrogen peroxide proved to be sporicidal (6 hours of exposure), mycobactericidal (20 minutes), fungicidal (5 minutes) at full strength, virucidal (5 minutes) and bactericidal (3 minutes) at a 1:16 dilution when a quantitative carrier test was used 655. The 7% solution of hydrogen peroxide, tested after 14 days of stress (in the form of germ-loaded carriers and respiratory therapy equipment), was sporicidal (>7 log10 reduction in 6 hours), mycobactericidal (>6.5 log10 reduction in 25 minutes), fungicidal (>5 log10 reduction in 20 minutes), bactericidal (>6 log10 reduction in 5 minutes) and virucidal (5 log10 reduction in 5 minutes) 663. Synergistic sporicidal effects were observed when spores were exposed to a combination of hydrogen peroxide (5.9%–23.6%) and peracetic acid 664. Other studies demonstrated the antiviral activity of hydrogen peroxide against rhinovirus 665. The time required for inactivating three serotypes of rhinovirus using a 3% hydrogen peroxide solution was 6–8 minutes; this time increased with decreasing concentrations (18-20 minutes at 1.5%, 50–60 minutes at 0.75%).
Concentrations of hydrogen peroxide from 6% to 25% show promise as chemical sterilants. The product marketed as a sterilant is a premixed, ready-to-use chemical that contains 7.5% hydrogen peroxide and 0.85% phosphoric acid (to maintain a low pH) 69. The mycobactericidal activity of 7.5% hydrogen peroxide has been corroborated in a study showing the inactivation of >105 multidrug-resistant M. tuberculosis after a 10-minute exposure 666. Thirty minutes were required for >99.9% inactivation of poliovirus and HAV 667. Three percent and 6% hydrogen peroxide were unable to inactivate HAV in 1 minute in a carrier test 58. When the effectiveness of 7.5% hydrogen peroxide at 10 minutes was compared with 2% alkaline glutaraldehyde at 20 minutes in manual disinfection of endoscopes, no significant difference in germicidal activity was observed 668. ). No complaints were received from the nursing or medical staff regarding odor or toxicity. In one study, 6% hydrogen peroxide (unused product was 7.5%) was more effective in the high-level disinfection of flexible endoscopes than was the 2% glutaraldehyde solution 456. A new, rapid-acting 13.4% hydrogen peroxide formulation (that is not yet FDA-cleared) has demonstrated sporicidal, mycobactericidal, fungicidal, and virucidal efficacy. Manufacturer data demonstrate that this solution sterilizes in 30 minutes and provides high-level disinfection in 5 minutes669. This product has not been used long enough to evaluate material compatibility to endoscopes and other semicritical devices, and further assessment by instrument manufacturers is needed.
Under normal conditions, hydrogen peroxide is extremely stable when properly stored (e.g., in dark containers). The decomposition or loss of potency in small containers is less than 2% per year at ambient temperatures 670.
Submitted by admin on Fri, 04/03/2020 - 12:21
In order to offer more information to our audience, the CDC has listed products that can be used on the latest coronavirus. Some brands are names, others are ingredients. Before reading the list, consider the ingredient for effectiveness and overall impact on applicators, workers, and buildings. In short, we want to see an effective sanitizing treatment that does not compromise the health of people while killing the dangerous infectious viruses.
Thymol: Made from the oil of Thyme and often mixed with alcohol for antiseptic treatments. Modest pH, and has few health concerns. The question of efficacy is whether the primary value is in the alcohol bases or the thyme oil.
Quaternary Ammonium: A cation. And referred to as "Quats". Basically they are long alkaline chains that are effective for treating many virus types except non-enveloping virus. Health concern is evidence of birth defects in laboratory tests.
Phenolic or Carbolic Acid: Made from coal tar, used as an antiseptic as far back as Joseph Lister. Phenol is corrosive to skin and mucous membranes. May affect heart and nervous system. Long term exposure could injure kidneys and liver.
Ethanol: Made from the fermentation of grains, commonly found in alcoholic drinks. Used in antiseptics and disinfecting products. Flammable. There are few health concerns.
Hydrogen Peroxide (H2O2) is a mild acidic solution with antiseptic properties. After application, hydrogen peroxide revert to water and oxygen. May bleach at higher concentrations, or may be corrosive on goods depending on strength of mixture and length of exposure.
Sodium Chlorite (NACIO2) is commonly used for bleaching and is a strong oxidant. May harm blood cells and kidneys. Termed a biocide.
Sodium Hypochlorite: (NACIO) and commonly called bleach. Offer broad-spectrum antimicrobial sanitizing. Dangerous when mixed with ammonia and other products. Produces high levels of VOC. Accidental spills may injure eyes and may damage skin.
Hypochlorous acid: (HOCI) a weak acid made when dissolving chlorine with water. An antiseptic or disinfectant. A strong oxidizing agent.
Sodium chlorite: (NaCIO2) a kind of chlorine dioxide often used for bleaching. A disinfectant used in commercial applications. Found to have long-term health concerns for blood and kidney problems.
Citric Acid: A weak acid derived from citrus fruits.
Submitted by admin on Fri, 12/27/2019 - 11:31
The Green Clean Institute is a respected third-party certification that assure that product claiming eco-friendly status are what they claim. We all know that there is a lot of latitude in advertising, and frankly, Green products tend to over-state their Green or eco-friendly attributes. So, when the Green Clean Institute approves a product, it has passed more than a clinical review. The GCI Green product certification reviews the claims made by a company to verify what is called a "Truth in Advertising for Green products."
Decon Five was always a Green and eco-friendly product. It is biodegradable and contains surfactants, hydrogen peroxide, and other inert ingredients in a very special blend not available elsewhere. The product is non-bleaching and about as corrosive as water. Once applied, the ingredients return to their inert status so that any excess will not harm waterways or fish.
Decon Five is pleased to be an approved Green product by the Green Clean Institute. In the remediation business, there are a lot of very powerful and dangerous chemicals. While they may do the jog, they offgas toxic fumes and leave a chemical residue. Decon Five does not offgas fumes or leave a toxic chemical residue. In fact, this unique blend will capture and neutralize all types of ambient VOC and chemical toxins in the building.
The secret is in the fact that Decon Five comes in two bottles (A and B) which are mixed 50/50 prior to application. This activates the product to full power without the need for strong chemical additives. After application, the product turns into water, oxygen, and inert ingredients that will not harm humans, pets, plants, or the environment.
Despite the safety of this product, it is amazingly effective on a number of levels. Decon Five is a very effective odor mitigation product. It also kills mold, mildew, the spores, and leaves a mildewstat to inhibit future mold growth. It will kill nearly all types of pathogens (bacteria and virus) with a seven log kill rate. Decon Five will neutralize all types of chemical residue to detoxify the building in a very effective way.
Decon Five will break the protein bonds of blood, urine, vomit, and body fluids for a powerful decontamination treatment. This is the ONE SOLUTION product that many specialty cleaning and decontamination services should be using.
Use Decon Five to remove curry smell from apartments, dog smell from homes, and get rid of smoke smell prior to the sale. The versatility of Decon Five can apply to carpets. Prespray with Decon Five and extract with a hot water carpet extractor. Or saturate a pet urine area down to the padding and subflloor to permanently get rid of stubborn pet odors. Wet vac the residue out after ten minutes.
Rarely has there been a ONE PRODUCT SOLUTION like Decon Five. The fact that this product is tremendously effective and still exceptionally safe seems to be what every service provider ought to adopt.
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